Vijay Sikand, MD
"We have a tremendous opportunity to inform both health care professionals and patients about the appropriate use of NSAIDs and their related risks."
Vijay Sikand, MD
Family Practice Physician
By promoting awareness of NSAID-associated risk and FDA NSAID dosing recommendations, I believe we can help decrease the incidence of serious NSAID-related adverse events.
—Vijay Sikand, MD
Family Practice Physician
In my practice, I probably see at least one patient a day who has experienced NSAID-related adverse events, ranging from upset stomach to cardiovascular thrombotic events.
—Vijay Sikand, MD
Family Practice Physician
It's the perfect pharmacotherapeutic storm. The opioid crisis may drive more and more physicians away from opioids toward other alternatives.
—Vijay Sikand, MD
Family Practice Physician
New low-dose NSAID formulations that are able to reduce systemic exposure and are efficacious should be of particular interest to health care professionals.
—Vijay Sikand, MD
Family Practice Physician
From my perspective as a cardiologist, we cannot ignore the potential link between NSAIDs and cardiovascular adverse events.
—William Hopkins, MD
Cardiologist
It's a common tendency in American life to want to super-size things. The disadvantages of super-sizing NSAID doses, however, are increased risks for developing serious gastrointestinal, cardiovascular, and renal adverse events.
—James Scheiman, MD
Gastroenterologist
Given the multifactorial nature of patient management, primary care providers must be diligent about screening for NSAID-related risks, even when these risks may not be obvious.
—Vijay Sikand, MD
Family Practice Physician
In the context of the current opioid epidemic, NSAIDs may become more important and relevant than ever.
—Vijay Sikand, MD
Family Practice Physician
Research has shown that after a certain dose threshold, the analgesic reaches a ceiling effect, so patients won’t necessarily experience any greater pain relief, but they may have greater potential risk for dose-related adverse events.
—James Scheiman, MD
Gastroenterologist
If I look back over the past 30 years of my career, I would have anticipated that awareness of dose-related NSAID risks would be a non-issue by now, because we’ve understood the problem. Despite the advances, it’s still something I see daily in my practice.
—Byron Cryer, MD
Gastroenterologist
From the patient's perspective, we need to be conscious of the fact that the pain is real and present for them, while the risk is less apparent.
—William Hopkins, MD
Cardiologist
These adverse events are not something that most physicians would necessarily think about, because it’s here in the ED that we see these events routinely. Other health care professionals may see them rarely, if at all.
—Charles Pollack, MD
Emergency Medicine Physician
The adverse events from NSAID use can be as glaring as a heart attack or as subtle as a tiny GI bleed.
—Charles Pollack, MD
Emergency Medicine Physician
We should be asking, 'What is the lowest dose of this NSAID that will relieve my patient's pain?'
—Charles Pollack, MD
Emergency Medicine Physician
It's all part of a shift in our larger understanding of how we as health care professionals and as a society not only help to manage pain, but manage it responsibly.
—William Hopkins, MD
Cardiologist
Download peer perspective white papers on the dose-related risk of certain serious adverse events associated with NSAID use.
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  • SIGN UP TO ACCESS 3 PEER PERSPECTIVE WHITE PAPERS

    Read about the most recent clinical strategies, data, and guidelines on how to minimize NSAID-associated risks:

    1. NSAIDs and Cardiovascular Risk: An Evolving Clinical Perspective by William Hopkins, MD
    2. NSAID-Associated Risks and the Changing Landscape of Pain Management by Vijay Sikand, MD
    3. NSAID-Induced Gastropathy: Clinical Challenges and Perspectives by Byron Cryer, MD

View video perspectives on NSAID use
Hear from experienced specialists and expert general practitioners about the dose-related risks of NSAIDs.
Cardiovascular Risks of NSAID Use
Cardiovascular Risks of NSAID Use
Dr. William Hopkins, Cardiologist
Dr. Hopkins’ expert opinion on the cardiovascular consequences of high NSAID doses.
Video Length 3:57
An Emergency Medicine Perspective on NSAID Use
An Emergency Medicine Perspective on NSAID Use
Dr. Charles Pollack, Emergency Medicine Physician
Insight from an emergency medicine physician who has seen the consequences of high NSAID doses.
Video Length 3:37
GI Risks of NSAID Use
GI Risks of NSAID Use
Dr. James Scheiman, Gastroenterologist
Expert insight on how certain serious adverse events go unnoticed, untreated, and unattributed to NSAIDs.
Video Length 3:48
Insights From an NSAID Expert
Insights From an NSAID Expert
Dr. Vijay Sikand, Family Practice Physician
Perspectives on responsible NSAID use from an emergency department physician turned family practice physician.
Video Length 4:13
References:

1. Data on File. Iroko Pharmaceuticals, LLC. 2016 HCP NSAID Survey. September 2016.